Kohtusairauskartoituksen tulokset julkaistiin huhtikuussa 2022 Journal of Exotic Pet Medicine -lehdessä. Lisäksi projektin ensimmäisistä tuloksista tehty posteri oli mukana toukokuussa 2019 ICARE 2019 -kongressissa Lontoossa.
Linkki artikkeliin (open access):
Mäkitaipale J, Airas N, Engblom S, Linden J.J Ex Pet Med 2022 41, 3-8.
Earlier studies indicate that the risk for uterine tumours in rabbits may be as high as 60–80%. This high occurrence and the need for routine neutering of non-breeding pet rabbits have recently been in the spotlight.Methods
This study aimed to describe and compare macroscopic and histopathological alterations in uteri collected from domestic rabbits of various ages neutered, deceased, or euthanized without a suspected uterine disorder (NoUD; n = 94) and from rabbits with a suspected uterine disorder (UD; n = 22).Results
In the NoUD group, uteri of 41 rabbits (44%) displayed histopathological findings and 12 rabbits (13%) had neoplasms. Samples from thirteen rabbits (14%) evinced histopathological findings with no macroscopic alterations. The most frequent diagnoses were cystic endometrial hyperplasia (26% of the 41 uteri), adenocarcinoma (9%), and polyps (5%). In the UD group, uteri from 21 (95%) out of 22 rabbits exhibited pathological alterations; in 2 (10%) of these, the changes (cystic endometrial hyperplasias) were seen only in histology. The most frequent diagnoses in the uteri of the UD group were cystic endometrial hyperplasia (77%) and adenocarcinoma (54%). Uterine malignant neoplasia affected 40% of all rabbits aged over 3 years, and the odds of a malignant uterine tumour in these rabbits were approximately 19-fold higher than in rabbits aged under 3 years.Conclusions and clinical relevance
Uterine disorders are common in domestic rabbits, even without a suspected uterine disease, and the risk of uterine neoplasia markedly increases after 3 years of age. A macroscopically normal uterus may have pathological changes and ovariohysterectomy should be therefore preferred over ovariectomy at least in older rabbits.